Author: Laine, Outi; Joutsi-Korhonen, Lotta; Lassila, Riitta; Huhtala, Heini; Vaheri, Antti; Mäkelä, Satu; Mustonen, Jukka
Title: Elevated thrombopoietin and platelet indices confirm active thrombopoiesis but fail to predict clinical severity of puumala hantavirus infection Document date: 2016_12_30
ID: jhcc6eex_9
Snippet: Serum samples to measure TPO level in the acute phase of the disease were collected median 8 days (range 2-13 days) from the beginning of fever. Citrated plasma for the measurement of procoagulant activity of MPs and coagulation variables (plasma fibrinogen, prothrombin fragments F1 + 2, and D-dimer) as well as whole blood for platelet indices (MPV and IPF%) and functions (PFA-100 and Multiplate) were all collected at the same time, median 7 days.....
Document: Serum samples to measure TPO level in the acute phase of the disease were collected median 8 days (range 2-13 days) from the beginning of fever. Citrated plasma for the measurement of procoagulant activity of MPs and coagulation variables (plasma fibrinogen, prothrombin fragments F1 + 2, and D-dimer) as well as whole blood for platelet indices (MPV and IPF%) and functions (PFA-100 and Multiplate) were all collected at the same time, median 7 days (range 1-12 days) from the beginning of fever. The control samples were obtained at the recovery visit, median 43 days (range 31-60 days) from the beginning of fever.
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