Selected article for: "acute phase and high level"
Author: Laine, Outi; Joutsi-Korhonen, Lotta; Lassila, Riitta; Huhtala, Heini; Vaheri, Antti; Mäkelä, Satu; Mustonen, Jukka
Title: Elevated thrombopoietin and platelet indices confirm active thrombopoiesis but fail to predict clinical severity of puumala hantavirus infection
  • Document date: 2016_12_30
    • ID: jhcc6eex_19
    Snippet: High serum TPO level coinciding still with thrombocytopenia associated with impaired platelet functions studied in whole blood by both PFA-100 (Fig. 2) and Multiplate in the acute phase of the disease. However, closure times studied with PFA-100 were only slightly prolonged acutely compared with the control despite the lowered platelet count ( Table 2) . Platelet functions studied with Multiplate are described in detail elsewhere. [10] High serum.....
    Document: High serum TPO level coinciding still with thrombocytopenia associated with impaired platelet functions studied in whole blood by both PFA-100 (Fig. 2) and Multiplate in the acute phase of the disease. However, closure times studied with PFA-100 were only slightly prolonged acutely compared with the control despite the lowered platelet count ( Table 2) . Platelet functions studied with Multiplate are described in detail elsewhere. [10] High serum TPO associated with impaired aggregation triggered with all 5 agonists (for adrenalin, r = À0.69, P < 0.001; for adenosine diphosphate, r = À0.77, P < 0.001; for arachidonic acid, r = À 0.67, P = 0.001; for collagen, r = À0.63, P = .002; for thrombin receptor-activating peptide, r = À0.50, P = .03; for ristocetin, r = À0.73, P < 0.001).

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