Author: Harlan Barker; Seppo Parkkila
Title: Bioinformatic characterization of angiotensin-converting enzyme 2, the entry receptor for SARS-CoV-2 Document date: 2020_4_13
ID: 08vsaov7_29
Snippet: Importantly, the lung specimens showed no significant difference of ACE2 mRNA expression between different age categories (p=0.681). Complete data on ACE mRNA expression levels in different age categories are shown in Supplementary Table 1. To make a binary comparison of expression by age, samples were divided into groups of ≤45 and >45 years of age. In comparison of these younger and older age groups, significant differences in expression were.....
Document: Importantly, the lung specimens showed no significant difference of ACE2 mRNA expression between different age categories (p=0.681). Complete data on ACE mRNA expression levels in different age categories are shown in Supplementary Table 1. To make a binary comparison of expression by age, samples were divided into groups of ≤45 and >45 years of age. In comparison of these younger and older age groups, significant differences in expression were found in tibial nerve (p=2.47 x 10 -7 ), whole blood (p=3.21 x 10 -4 ), minor salivary gland (p=4.89 x 10 -4 ), sun exposed skin (p=0.003), transverse colon (p=0.022), testis (p=0.025), esophageal muscle layer (p=0.040), and subcutaneous adipose tissue (p=0.045).
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