Selected article for: "delivery system and vaccine delivery system"
Author: Jain, K.K.
Title: Synthetic Biology and Personalized Medicine
  • Document date: 2012_8_16
    • ID: jejgkcql_59
    Snippet: The use of liposomes has been proposed as artificial microbes for vaccination as they can be genetically programmed to produce specific antigens at will [33] . Studies in mice with such vaccines showed that antigen-expressing immunostimulatory liposomes (AnExILs) elicited higher specific humoral immune responses against the produced antigens than control vaccines. AnExILs can be used as a synthetic biology platform to construct DNAbased vaccines,.....
    Document: The use of liposomes has been proposed as artificial microbes for vaccination as they can be genetically programmed to produce specific antigens at will [33] . Studies in mice with such vaccines showed that antigen-expressing immunostimulatory liposomes (AnExILs) elicited higher specific humoral immune responses against the produced antigens than control vaccines. AnExILs can be used as a synthetic biology platform to construct DNAbased vaccines, which combines antigen production, adjuvants and delivery in one system, offering several advantages over existing vaccine formulations. This system can be easily altered for other antigens by simply changing the DNA template and carries no risk of infection by attenuated pathogens.

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