Author: Hendaus, Mohamed A; Jomha, Fatima A; Alhammadi, Ahmed H
Title: Virus-induced secondary bacterial infection: a concise review Document date: 2015_8_24
ID: k7eo2c26_16
Snippet: MxA blood values were calculated in infants and children with verified bacterial or viral infections, uninfected controls, and infections of unknown origin. A receiver operating characteristic analysis was used to verify the diagnostic performance of MxA. The study, which included 553 children, showed that MxA was significantly higher in children with viral versus bacterial infections and uninfected controls (P0.0001). Additionally, MxA levels.....
Document: MxA blood values were calculated in infants and children with verified bacterial or viral infections, uninfected controls, and infections of unknown origin. A receiver operating characteristic analysis was used to verify the diagnostic performance of MxA. The study, which included 553 children, showed that MxA was significantly higher in children with viral versus bacterial infections and uninfected controls (P0.0001). Additionally, MxA levels were significantly higher in children with clinically diagnosed viral infections than in those with clinically diagnosed bacterial infections (P0.001). 79 Other authors have also reported the usefulness of blood MxA testing in patients with viral infections. 80, 81 The use MxA in diagnosing viral infection is very promising, especially in patients who are at risk of infectious complications. Two separate studies have shown that blood MxA is beneficial in differentiating between viral illness and acute graft-versushost disease after allogenic stem cell transplantation. 82, 83
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