Selected article for: "human expression and viral infection"

Author: Bautista-Hernández, Luis Antonio; Gómez-Olivares, José Luis; Buentello-Volante, Beatriz; Bautista-de Lucio, Victor Manuel
Title: Fibroblasts: The Unknown Sentinels Eliciting Immune Responses Against Microorganisms
  • Document date: 2017_8_19
  • ID: j4lfwdbh_40
    Snippet: The production of growth factors by fi broblasts has also been reported [47] . According to Herath's study, P. gin givalis induced the expression of GM-CSF in human gingival fi broblasts [16] , and Lu et al. [49] observed the synthesis of GMC-CSF in corneal fi broblasts when stimulated by P. aeruginosa LPS, while Dominguez-Lopez reported poly I:C-induced G-CSF expression on limbo-corneal myofi broblasts [23] . These reports permit us to conclude .....
    Document: The production of growth factors by fi broblasts has also been reported [47] . According to Herath's study, P. gin givalis induced the expression of GM-CSF in human gingival fi broblasts [16] , and Lu et al. [49] observed the synthesis of GMC-CSF in corneal fi broblasts when stimulated by P. aeruginosa LPS, while Dominguez-Lopez reported poly I:C-induced G-CSF expression on limbo-corneal myofi broblasts [23] . These reports permit us to conclude that the fi broblast produces GM-CSF upon bacterial stimulation and G-CSF in a viral infection. These growth factors indicate that the fi broblasts recruit infl ammatory cells in response to microorganisms and induce cellular proliferation (Table 1) .

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