Author: Lv, Lishan; Li, Xiaoming; Liu, Genmei; Li, Ran; Liu, Qiliang; Shen, Huifang; Wang, Wei; Xue, Chunyi; Cao, Yongchang
Title: Production and immunogenicity of chimeric virus-like particles containing the spike glycoprotein of infectious bronchitis virus Document date: 2014_6_16
ID: k785hl1r_38
Snippet: Serum S1-specific IgG antibody titers were determined by ELISA, which showed that chimeric VLPs were as efficient at stimulating total anti-S1 antibodies as inactivated viruses (Fig. 6) . The chimeric VLP group and the inactivated H120 viruses group both exhibited a higher level of antibodies than the PBS control group (p ＜ 0.01). Additionally, the level of antibodies of the chimeric VLP group was higher than that of the H120 group (p ＜ 0.05).....
Document: Serum S1-specific IgG antibody titers were determined by ELISA, which showed that chimeric VLPs were as efficient at stimulating total anti-S1 antibodies as inactivated viruses (Fig. 6) . The chimeric VLP group and the inactivated H120 viruses group both exhibited a higher level of antibodies than the PBS control group (p ＜ 0.01). Additionally, the level of antibodies of the chimeric VLP group was higher than that of the H120 group (p ＜ 0.05).
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