Selected article for: "International license and significantly high score"
Author: Joana Damas; Graham M. Hughes; Kathleen C. Keough; Corrie A. Painter; Nicole S. Persky; Marco Corbo; Michael Hiller; Klaus-Peter Koepfli; Andreas R. Pfenning; Huabin Zhao; Diane P. Genereux; Ross Swofford; Katherine S. Pollard; Oliver A. Ryder; Martin T. Nweeia; Kerstin Lindblad-Toh; Emma C. Teeling; Elinor K. Karlsson; Harris A. Lewin
Title: Broad Host Range of SARS-CoV-2 Predicted by Comparative and Structural Analysis of ACE2 in Vertebrates
  • Document date: 2020_4_18
    • ID: 6ne76rh1_62
    Snippet: . CC-BY-NC-ND 4.0 International license author/funder. It is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.16.045302 doi: bioRxiv preprint Figure 2 . Congruence between binding score and structural homology analysis. Species classified by sequence identity to human ACE2 as very high (red) or high binding score (orange) have significantly fewer amino acid substi.....
    Document: . CC-BY-NC-ND 4.0 International license author/funder. It is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.16.045302 doi: bioRxiv preprint Figure 2 . Congruence between binding score and structural homology analysis. Species classified by sequence identity to human ACE2 as very high (red) or high binding score (orange) have significantly fewer amino acid substitutions rated as potentially altering the binding interface between ACE2 and SARS-CoV-2 through protein structural analysis, as compared to low (green) or very low (blue) species. The more severe unfavorable variants are counted on y-axis and less severe weaken variants on the x-axis. Black numerical labels indicate species count.

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