Author: Luo, Cheng-Xin; Wen, Zhong-Hui; Zhen, Yu; Wang, Zhu-Jun; Mu, Jing-Xi; Zhu, Min; Ouyang, Qin; Zhang, Hu
Title: Chinese research into severe ulcerative colitis has increased in quantity and complexity Document date: 2018_3_16
ID: jmjtr1pb_17
Snippet: Management is the prime focus of SUC related clinical research. Sixteen of the 21 observational analytical studies and all of the 36 clinical trials focused on the medical management of SUC (median sample size of 64). Treatment types included Traditional Chinese Medicine (46.2%), corticosteroid therapy (17.3%), enteral or parenteral nutrition support (11.5%), immunosuppressive drugs (7.7%), biological agents (3.8%), probiotics (5.7%) and others (.....
Document: Management is the prime focus of SUC related clinical research. Sixteen of the 21 observational analytical studies and all of the 36 clinical trials focused on the medical management of SUC (median sample size of 64). Treatment types included Traditional Chinese Medicine (46.2%), corticosteroid therapy (17.3%), enteral or parenteral nutrition support (11.5%), immunosuppressive drugs (7.7%), biological agents (3.8%), probiotics (5.7%) and others (7.7%) ( Figure 6 ). Adjunctive therapy with Traditional Chinese Medicine was studied in 55.6% (20/36) of clinical trials with the effective rates ranging from 73% to 97%, with 12 articles reporting an effective rate of more than 90%. The most commonly used herbs were Radix Pulsatillae, Radix Scutellariae, Rhizoma Coptidis, Radix Paeoniae Rubra, and Radix Puerariae and the most commonly used formulation was a modified Pulsatilla decoction.
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