Author: Mammas, Ioannis N.; Greenough, Anne; Theodoridou, Maria; Kramvis, Anna; Rusan, Maria; Melidou, Angeliki; Korovessi, Paraskevi; Papaioannou, Georgia; Papatheodoropoulou, Alexia; Koutsaftiki, Chryssie; Liston, Maria; Sourvinos, George; Spandidos, Demetrios A.
Title: Paediatric Virology and its interaction between basic science and clinical practice (Review) Document date: 2018_1_4
ID: ix314s4n_39
Snippet: Asthma has been considered for >30 years as the most common chronic disease in childhood (95, 96) ; the role of allergy in its development is indeed very significant (97) . Other risk factors that have also been associated with the pathogenesis of asthma include prematurity, parental history of asthma, reduced lung size and function, chronic lung disease, neuromuscular or cardiovascular disease, the male sex, low socioeconomic status, down syndro.....
Document: Asthma has been considered for >30 years as the most common chronic disease in childhood (95, 96) ; the role of allergy in its development is indeed very significant (97) . Other risk factors that have also been associated with the pathogenesis of asthma include prematurity, parental history of asthma, reduced lung size and function, chronic lung disease, neuromuscular or cardiovascular disease, the male sex, low socioeconomic status, down syndrome, intrauterine tobacco smoke exposure and passive smoking, daycare attendance, early exposure to pets, as well as viral respiratory tract infections in infancy (96, (98) (99) (100) . Among these factors, infections, such as acute viral bronchiolitis, caused by RSV and RV in particular, have been recognised as one of the most significant predictive markers for the development of asthma in later childhood to young adulthood (99) (100) (101) (102) .
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