Effect of acute respiratory infections in infancy on pulmonary function test at 3 years of age: a prospective birth cohort study

Kumar, Prawin; Mukherjee, Aparna; Randev, Shivani; Medigeshi, Guruprasad R; Jat, Kana Ram; Kapil, Arti; Lodha, Rakesh; Kabra, Sushil Kumar

Most of the available literature mainly focuses on alteration in pulmonary function test in school children with a history of LRTI, bronchiolitis or RSV/RV infection during , forced expiratory flow between 25% and 75% of FVC; FEV, forced expiratory volume; FEV 0.5 , FEV 0.75 , FEV 1.0 , forced expiratory volume in 0.5/0.75/1 s; IPFT, infant pulmonary function test; MEF 25 /MEF 10 , maximum expiratory flow at 25% or 10% of FVC; MTEF, mid tidal expiratory flow; PEF, peak expiratory flow; PTEF, peak tidal expiratory flow; RTC, rapid thoracoabdominal compression; RVRTC, raised volume rapid thoracoabdominal compression; TBFVL, tidal breathing flow-volume loop; TEF 10 or TEF 25 or TEF 50 /PTEF, the ratio of TEF 10 , TEF 25 or TEF 50 to peaked tidal expiratory flow; TEF 10 /TEF 25 /TEF 50 , tidal expiratory flow when 10%/25%/50% of tidal volume remaining for expiration; t E /t tot , ratio of expiratory time to total respiratory time; t PTEF /t E , the ratio of time to peak tidal expiratory flow to total expiratory time; Vʹ max, FRC , maximal flow at functional residual capacity; V PTEF /V E , ratio of exhaled volume to PTEF to tidal expiratory volume; V T , tidal volume; VT/kg, tidal volume per unit bodyweight.