Author: KANEGI, Ryoji; YASUGI, Mayo; NABETANI, Tomoyo; TANAKA, Toshiyuki; WADA, Yusuke; HIRAI, Kotaro; SUGIURA, Kikuya; HATOYA, Shingo
Title: Clinical findings and treatment of disseminated ‘Mycobacterium avium subspecies hominissuis’ infection in a domestic cat Document date: 2019_10_31
ID: kjpmh3ap_3
Snippet: Here, we diagnosed MAH infection in a domestic cat who was referred because of lung disease of an unknown origin. During clinical investigation, we detected an interstitial lung pattern, a swollen abdominal lymph node, and multiple nodules of the liver. Cytology of the lymph node and the liver indicated signs of granulomatous inflammation without any bacteria. However, cultures of bronchus and liver FNA specimens were positive for NTM, which was .....
Document: Here, we diagnosed MAH infection in a domestic cat who was referred because of lung disease of an unknown origin. During clinical investigation, we detected an interstitial lung pattern, a swollen abdominal lymph node, and multiple nodules of the liver. Cytology of the lymph node and the liver indicated signs of granulomatous inflammation without any bacteria. However, cultures of bronchus and liver FNA specimens were positive for NTM, which was confirmed as MAH through SNP analysis and analysis of the phylogenetic tree of hsp65. After the administration of combination antibiotics for 6 months, NTM culture of bronchial and liver FNA specimens results turned negative. We stopped administration of antibiotics after an additional 6 months, and there were no signs of relapse on day 771 of illness.
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