Selected article for: "frameshift efficiency and overall stability"
Author: Mouzakis, Kathryn D.; Lang, Andrew L.; Vander Meulen, Kirk A.; Easterday, Preston D.; Butcher, Samuel E.
Title: HIV-1 frameshift efficiency is primarily determined by the stability of base pairs positioned at the mRNA entrance channel of the ribosome
  • Document date: 2012_12_15
    • ID: ix8du1er_22
    Snippet: Frameshift efficiency was plotted as a function of overall and local thermodynamic stability. Overall and local thermodynamic stabilities were predicted at 1 M NaCl. Data were fit to a one-phase exponential decay function [Equation (5)] (Prism 4.3, GraphPad). Here, the Amplitude, K and Plateau are variables and X o is used to offset the exponential fit. X o was set to the most negative X value in the data set. Errors were determined using a 95% c.....
    Document: Frameshift efficiency was plotted as a function of overall and local thermodynamic stability. Overall and local thermodynamic stabilities were predicted at 1 M NaCl. Data were fit to a one-phase exponential decay function [Equation (5)] (Prism 4.3, GraphPad). Here, the Amplitude, K and Plateau are variables and X o is used to offset the exponential fit. X o was set to the most negative X value in the data set. Errors were determined using a 95% confidence interval.

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