Author: Qingyang Xu; Shomesh Chaudhuri; Danying Xiao; Andrew W Lo
Title: Bayesian Adaptive Clinical Trials for Anti-Infective Therapeutics during Epidemic Outbreaks Document date: 2020_4_14
ID: 20hk99h4_69
Snippet: To provide transparency for how a patient-centered approach differs from the traditional statistical framework in the anti-infectives context, we used a relatively simple mathematical model of epidemic disease dynamics to estimate the societal loss in an outbreak. More sophisticated epidemiological models can easily be incorporated into our framework at the cost of computational tractability and transparency......
Document: To provide transparency for how a patient-centered approach differs from the traditional statistical framework in the anti-infectives context, we used a relatively simple mathematical model of epidemic disease dynamics to estimate the societal loss in an outbreak. More sophisticated epidemiological models can easily be incorporated into our framework at the cost of computational tractability and transparency.
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