Chinese research into severe ulcerative colitis has increased in quantity and complexity

Luo, Cheng-Xin; Wen, Zhong-Hui; Zhen, Yu; Wang, Zhu-Jun; Mu, Jing-Xi; Zhu, Min; Ouyang, Qin; Zhang, Hu

In conclusion, our study documents that significant progress has occurred in SUC research within the Chinese medical research community, as reflected by the increased output and complexity of publications. Although Traditional Chinese Medicine has been widely used as a complementary therapy for SUC, rigorous experiments and careful analysis of the resulting experimental data are required to validate the benefit and safety of this type of treatment. The relatively few publications into salvage therapy suggest that more research into the efficacy of treatment with cyclosporin or infliximab in Chinese SUC patients is required. We reported a male predominance in SUC incidence and a lower colectomy rate in Chinese SUC patients compared to western countries based on literature review. Data of clinical characteristics obtained from our literature review should be verified and extended by further welldesigned and detailed population-based studies.