Author: Holmes, Kathryn V.; Dominguez, Samuel R.
Title: The New Age of Virus Discovery: Genomic Analysis of a Novel Human Betacoronavirus Isolated from a Fatal Case of Pneumonia Document date: 2013_1_8
ID: krvei97r_3
Snippet: What can analysis of its RNA genome tell us about this new human coronavirus? Analysis of the HCoV-EMC genome was able to distinguish whether HCoV-EMC was a known human coronavirus with mutations that increased its virulence or a product of recombination between two or more known coronavirus species or, like SARS-CoV, a spillover of a zoonotic coronavirus that was transmitted, either directly or indirectly, to humans from an animal reservoir. The.....
Document: What can analysis of its RNA genome tell us about this new human coronavirus? Analysis of the HCoV-EMC genome was able to distinguish whether HCoV-EMC was a known human coronavirus with mutations that increased its virulence or a product of recombination between two or more known coronavirus species or, like SARS-CoV, a spillover of a zoonotic coronavirus that was transmitted, either directly or indirectly, to humans from an animal reservoir. The genomic analysis showed that HCoV-EMC is a new coronavirus that had never before been detected in any other species.
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