Author: Delli Ponti, Riccardo; Marti, Stefanie; Armaos, Alexandros; Tartaglia, Gian Gaetano
Title: A high-throughput approach to profile RNA structure Document date: 2017_3_17
ID: k23xlzj0_14
Snippet: We combined the five CROSS models into a Z-Score variable. For each nucleotide in the sequence, the Z-Score is computed using the mean of the individual scores and the associated standard deviation: the double-stranded propensity is proportional to the Z-Score. We used this method to predict the structural profile of the Xist non-coding RNA (17 900 nt) and found an AUC of 0.75 on data from DMS experiments (16) ......
Document: We combined the five CROSS models into a Z-Score variable. For each nucleotide in the sequence, the Z-Score is computed using the mean of the individual scores and the associated standard deviation: the double-stranded propensity is proportional to the Z-Score. We used this method to predict the structural profile of the Xist non-coding RNA (17 900 nt) and found an AUC of 0.75 on data from DMS experiments (16) .
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