Author: Lee, Jeongmin; Kim, Su Yeon; Hwang, Kyu Jam; Ju, Young Ran; Woo, Hee-Jong
Title: Prion Diseases as Transmissible Zoonotic Diseases Document date: 2013_2_23
ID: kpubzqzw_31
Snippet: However, authorized tests that use antigeneantibody reactions are good for highly concentrated specimens, such as the brain and spinal cord, since the amount detectable by ELISA-based procedures is so low that they cannot be applied to actual blood specimens, through which the disease can be transmitted. Therefore, many scientific efforts have been made to overcome this shortcoming, such as protein misfolding cyclic amplification, which uses the .....
Document: However, authorized tests that use antigeneantibody reactions are good for highly concentrated specimens, such as the brain and spinal cord, since the amount detectable by ELISA-based procedures is so low that they cannot be applied to actual blood specimens, through which the disease can be transmitted. Therefore, many scientific efforts have been made to overcome this shortcoming, such as protein misfolding cyclic amplification, which uses the replication of the conformation of a protein [65] , and real-time immuno-polymerase chain Formalin-fixed brain tissue Spongiform in brain tissue Immunohistochemistry
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