Author: Kanagalingam, J.; Feliciano, R.; Hah, J. H.; Labib, H.; Le, T. A.; Lin, J.-C.
Title: Practical use of povidone-iodine antiseptic in the maintenance of oral health and in the prevention and treatment of common oropharyngeal infections Document date: 2015_8_6
ID: jiblk5qp_32
Snippet: The pathogenesis of oral mucositis involves direct and indirect mechanisms. Direct mucosal injury by radiation and chemotherapy interfere with the average 5-to 14-day turnover time of the oral epithelium and induce apoptosis. Indirect stomatotoxic effects that result from the release of inflammatory mediators, loss of protective salivary constituents and therapy-induced neutropenia have been postulated to contribute to the development of oral muc.....
Document: The pathogenesis of oral mucositis involves direct and indirect mechanisms. Direct mucosal injury by radiation and chemotherapy interfere with the average 5-to 14-day turnover time of the oral epithelium and induce apoptosis. Indirect stomatotoxic effects that result from the release of inflammatory mediators, loss of protective salivary constituents and therapy-induced neutropenia have been postulated to contribute to the development of oral mucositis and also to promote the emergence of bacteria, fungi and viruses on damaged mucosa (82) .
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