Title: Atti del 52° Congresso Nazionale: Società Italiana di Igiene, Medicina Preventiva e Sanità Pubblica (SItI) Document date: 2019_10_15
ID: jkke8ije_319
Snippet: In Apulia region, VC estimated from 16 birth cohorts included 657,978 individuals aged 7-22 years in 2018: 537,737 have received two doses of measles vaccine and 120,241 were still unvaccinated. From October 2018 to March 2019, at least two outbreaks have occurred in Apulia, counting 10 confirmed cases of measles in the age group studied. By assuming unvaccinated individuals (n = 7), as a control of measuring background infectivity, and 2-dose va.....
Document: In Apulia region, VC estimated from 16 birth cohorts included 657,978 individuals aged 7-22 years in 2018: 537,737 have received two doses of measles vaccine and 120,241 were still unvaccinated. From October 2018 to March 2019, at least two outbreaks have occurred in Apulia, counting 10 confirmed cases of measles in the age group studied. By assuming unvaccinated individuals (n = 7), as a control of measuring background infectivity, and 2-dose vaccinated individuals (n = 3), the VE was estimated to be about 90%. For the median of the Bayesian posterior distribution we obtained VE = 0.9013 close to the maximum likelihood estimator of 90.4% and as upper 95%-CI boundary VE = 0.977. The lower boundary was 0.659.
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