Selected article for: "biological process and enriched process"
Author: Harlan Barker; Seppo Parkkila
Title: Bioinformatic characterization of angiotensin-converting enzyme 2, the entry receptor for SARS-CoV-2
  • Document date: 2020_4_13
    • ID: 08vsaov7_8
    Snippet: In each of the tissues present in the GTEx dataset, expression values for ACE2 were compared with expression of all other genes by Spearman correlation analysis using the SciPy (34) Python library to identify those genes with concordant expression patterns. Bonferroni correction was used to derive an adjusted p-value threshold of 9.158E-07. For each tissue, those genes which both satisfied the Bonferroni-adjusted p-value threshold and had a corre.....
    Document: In each of the tissues present in the GTEx dataset, expression values for ACE2 were compared with expression of all other genes by Spearman correlation analysis using the SciPy (34) Python library to identify those genes with concordant expression patterns. Bonferroni correction was used to derive an adjusted p-value threshold of 9.158E-07. For each tissue, those genes which both satisfied the Bonferroni-adjusted p-value threshold and had a correlation of expression of 0.50 or greater were analyzed using the Gprofiler gene ontology (GO) enrichment analysis (35) Python library to identify possible enriched terms in biological process (BP), molecular function (MF), cellular component (CC), human phenotype (HP), KEGG pathway, and WikiPathways (WP) ontologies.

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