Selected article for: "immune response and surface protein"
Author: Lv, Lishan; Li, Xiaoming; Liu, Genmei; Li, Ran; Liu, Qiliang; Shen, Huifang; Wang, Wei; Xue, Chunyi; Cao, Yongchang
Title: Production and immunogenicity of chimeric virus-like particles containing the spike glycoprotein of infectious bronchitis virus
  • Document date: 2014_6_16
    • ID: k785hl1r_43
    Snippet: In summary, this study demonstrated the generation of a chimeric VLP by expression of the IBV S1 protein on the surface of influenza VLPs. The results showed that the chimeric VLPs could elicit humoral and cellular immune responses and neutralization antibody response at a level significantly higher than that of inactivated IBV viruses. Accordingly, chimeric VLPs are a potential candidate for the development of vaccines against IBV......
    Document: In summary, this study demonstrated the generation of a chimeric VLP by expression of the IBV S1 protein on the surface of influenza VLPs. The results showed that the chimeric VLPs could elicit humoral and cellular immune responses and neutralization antibody response at a level significantly higher than that of inactivated IBV viruses. Accordingly, chimeric VLPs are a potential candidate for the development of vaccines against IBV.

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