Author: Peri, Sateesh; Kulkarni, Asmita; Feyertag, Felix; Berninsone, Patricia M; Alvarez-Ponce, David
Title: Phylogenetic Distribution of CMP-Neu5Ac Hydroxylase (CMAH), the Enzyme Synthetizing the Proinflammatory Human Xenoantigen Neu5Gc Document date: 2017_12_30
ID: k596omcy_29
Snippet: We identified CMAH homologous sequences in all the studied cephalochordates, including one copy in Asymmetron lucayanum (Bahama lancelet), five in Branchiostoma belcheri (Chinese amphioxus), and seven in Branchiostoma floridae (Floridan amphioxus). One of the B. belcheri copies had a premature stop codon in coding exon 6, and one of the B. floridae copies had a premature stop codon in coding exon 13. Our results are in agreement with a previous r.....
Document: We identified CMAH homologous sequences in all the studied cephalochordates, including one copy in Asymmetron lucayanum (Bahama lancelet), five in Branchiostoma belcheri (Chinese amphioxus), and seven in Branchiostoma floridae (Floridan amphioxus). One of the B. belcheri copies had a premature stop codon in coding exon 6, and one of the B. floridae copies had a premature stop codon in coding exon 13. Our results are in agreement with a previous report of Neu5Gc in B. belcheri (belcher's lancelet) (Gué rardel et al. 2012).
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