Selected article for: "active recombination display and adaptive potential"

Author: Domingo, Esteban
Title: Mechanisms of viral emergence
  • Document date: 2010_2_5
  • ID: k6v4am7l_17
    Snippet: Interestingly, despite the obvious impact of recombination for viral evolution [14, 41, 57] , some negative-strand RNA viruses do not seem to display an active recombination, at least among standard infectious genomes. These viruses show, however, an extremely high adaptive potential comparable to that of other RNA viruses that display an active recombination [61] . This suggests that the viruses that have survived to the present time, and probab.....
    Document: Interestingly, despite the obvious impact of recombination for viral evolution [14, 41, 57] , some negative-strand RNA viruses do not seem to display an active recombination, at least among standard infectious genomes. These viruses show, however, an extremely high adaptive potential comparable to that of other RNA viruses that display an active recombination [61] . This suggests that the viruses that have survived to the present time, and probably also their ancestors, have redundant adaptive mechanisms to respond to the multiple selective constraints that their hosts have evolved to limit their replication. All mechanisms of genetic variation of viruses exert a key influence in viral disease emergence, as discussed next.

    Search related documents:
    Co phrase search for related documents
    • adaptive mechanism and RNA virus: 1
    • disease emergence and genetic variation: 1, 2, 3, 4, 5
    • disease emergence and negative strand: 1, 2
    • disease emergence and present time: 1, 2
    • disease emergence and RNA virus: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12
    • genetic variation and key influence: 1
    • genetic variation and replication limit: 1
    • genetic variation and RNA virus: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
    • infectious genome and negative strand: 1, 2
    • infectious genome and RNA virus: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18
    • negative strand and present time: 1
    • negative strand and probably ancestor: 1
    • negative strand and replication limit: 1
    • negative strand and RNA virus: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • negative strand RNA virus and RNA virus: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • present time and RNA virus: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16
    • probably ancestor and RNA virus: 1