Author: Joana Damas; Graham M. Hughes; Kathleen C. Keough; Corrie A. Painter; Nicole S. Persky; Marco Corbo; Michael Hiller; Klaus-Peter Koepfli; Andreas R. Pfenning; Huabin Zhao; Diane P. Genereux; Ross Swofford; Katherine S. Pollard; Oliver A. Ryder; Martin T. Nweeia; Kerstin Lindblad-Toh; Emma C. Teeling; Elinor K. Karlsson; Harris A. Lewin
Title: Broad Host Range of SARS-CoV-2 Predicted by Comparative and Structural Analysis of ACE2 in Vertebrates Document date: 2020_4_18
ID: 6ne76rh1_9
Snippet: Comparative analysis of ACE2 nucleotide and protein sequences can predict their ability to bind SARS-CoV-2 S and therefore will yield important insights into the biology and potential zoonotic transmission of SARS-CoV-2 infection. Recent work has examined ACE2 from different vertebrate species and predicted its ability to bind SARS-CoV-2 S, but phylogenetic sampling was extremely limited (11, 23) ......
Document: Comparative analysis of ACE2 nucleotide and protein sequences can predict their ability to bind SARS-CoV-2 S and therefore will yield important insights into the biology and potential zoonotic transmission of SARS-CoV-2 infection. Recent work has examined ACE2 from different vertebrate species and predicted its ability to bind SARS-CoV-2 S, but phylogenetic sampling was extremely limited (11, 23) .
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