Author: Noh, Heeju; Shoemaker, Jason E; Gunawan, Rudiyanto
Title: Network perturbation analysis of gene transcriptional profiles reveals protein targets and mechanism of action of drugs and influenza A viral infection Document date: 2018_4_6
ID: j80hnhpb_17
Snippet: While the regulatory edges in the model above usually describe TF-gene interactions, in ProTINA, we further accounted for the (indirect) regulation of a gene by proteins that interact with the TFs. For this purpose, we considered a modified ODE model:.....
Document: While the regulatory edges in the model above usually describe TF-gene interactions, in ProTINA, we further accounted for the (indirect) regulation of a gene by proteins that interact with the TFs. For this purpose, we considered a modified ODE model:
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