Author: Jain, K.K.
Title: Synthetic Biology and Personalized Medicine Document date: 2012_8_16
ID: jejgkcql_22
Snippet: Since several complex diseases are caused by disorders of human metabolism, elucidation of the underlying molecular mechanisms is important for developing an effective and personalized approach for their treatment. Systems biology can facilitate the analysis of complex metabolic diseases by use of computational approaches. A systems medicine approach can utilize such data about metabolic processes to reconstruct genome-scale metabolic models for .....
Document: Since several complex diseases are caused by disorders of human metabolism, elucidation of the underlying molecular mechanisms is important for developing an effective and personalized approach for their treatment. Systems biology can facilitate the analysis of complex metabolic diseases by use of computational approaches. A systems medicine approach can utilize such data about metabolic processes to reconstruct genome-scale metabolic models for study of the function of specific enzymes and pathways in the context of the complete metabolic network. Reconstruction of genome-scale models in systems medicine may contribute towards the development of personalized medicine for human metabolic disorders [13] .
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