Author: Lam, Yun W.; Evans, Vanessa C.; Heesom, Kate J.; Lamond, Angus I.; Matthews, David A.
Title: Proteomics Analysis of the Nucleolus in Adenovirus-infected Cells Document date: 2009_10_7
ID: jgxbpy4j_30
Snippet: Thus, adenovirus infection induces a change in the nucleolar proteome that is distinct from the classical nucleolar disruption caused either by transcription inhibition or by other general cellular stresses. Viral infection in this case induces a much more limited and targeted effect on the nucleolar proteome. Moreover, the 2D approach reinforces the observation from SILAC analysis that adenovirus infection does not induce.....
Document: Thus, adenovirus infection induces a change in the nucleolar proteome that is distinct from the classical nucleolar disruption caused either by transcription inhibition or by other general cellular stresses. Viral infection in this case induces a much more limited and targeted effect on the nucleolar proteome. Moreover, the 2D approach reinforces the observation from SILAC analysis that adenovirus infection does not induce
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