Selected article for: "alveolar recruitment and oxygenation improve"
Author: Bein, Thomas; Grasso, Salvatore; Moerer, Onnen; Quintel, Michael; Guerin, Claude; Deja, Maria; Brondani, Anita; Mehta, Sangeeta
Title: The standard of care of patients with ARDS: ventilatory settings and rescue therapies for refractory hypoxemia
  • Document date: 2016_4_4
    • ID: krpg9u1u_19
    Snippet: Alveolar recruitment, obtained through positive endexpiratory pressure (PEEP) and/or lung recruiting maneuvers (LRMs), has been used to improve hypoxemia in patients with ARDS since the early 1970s, just after the first description of the syndrome [30] . At present, the aim of alveolar recruitment is not only to improve oxygenation but also to prevent VALI by minimizing tidal alveolar opening and collapse (atelectrauma) [31] . However, despite a .....
    Document: Alveolar recruitment, obtained through positive endexpiratory pressure (PEEP) and/or lung recruiting maneuvers (LRMs), has been used to improve hypoxemia in patients with ARDS since the early 1970s, just after the first description of the syndrome [30] . At present, the aim of alveolar recruitment is not only to improve oxygenation but also to prevent VALI by minimizing tidal alveolar opening and collapse (atelectrauma) [31] . However, despite a myriad of clinical and translational studies and three large clinical trials, the effectiveness of recruitment remains controversial [32] [33] [34] [35] . One "simple" reason is that clinicians lack bedside methods to quantify alveolar recruitment and its impact on VILI. Hence, decisions are based on surrogates, such as arterial oxygenation, endinspiratory plateau pressure, or driving pressure. Electrical impedance tomography (EIT), lung ultrasound, and the stress index have been proposed to monitor alveolar recruitment, but are seldom used in clinical practice [11, 36] .

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