Selected article for: "bioinformatic analysis and Ebola virus"
Author: Penno, Christophe; Kumari, Romika; Baranov, Pavel V.; van Sinderen, Douwe; Atkins, John F.
Title: Stimulation of reverse transcriptase generated cDNAs with specific indels by template RNA structure: retrotransposon, dNTP balance, RT-reagent usage
  • Document date: 2017_9_29
    • ID: k4gtl2o7_2
    Snippet: Evolutionary selected transcription slippage is utilized in the expression of viruses such as the Paramyxoviruses, Sendai virus and Parainfluenza virus (3, 4) , the Filovirus, Ebola virus (5) (6) (7) , the large Potyviridae family (8-10), chromosomal genes such as Thermus thermophilus dnaX (11) , numerous genes in an endosymbiont (12) , a variety of bacterial Insertion Sequences (13) (14) (15) (16) , several medically important plasmid genes of S.....
    Document: Evolutionary selected transcription slippage is utilized in the expression of viruses such as the Paramyxoviruses, Sendai virus and Parainfluenza virus (3, 4) , the Filovirus, Ebola virus (5) (6) (7) , the large Potyviridae family (8-10), chromosomal genes such as Thermus thermophilus dnaX (11) , numerous genes in an endosymbiont (12) , a variety of bacterial Insertion Sequences (13) (14) (15) (16) , several medically important plasmid genes of Shigella flexneri (17) (18) (19) , and counterpart chromosomal toxin secretion genes in Citrobacter rodentium and Yersinia pseudotuberculosis (20) . Further, an extensive bioinformatic analysis of bacterial genomes has revealed many candidates that have yet to be experimentally explored (13, 15, 16) . Transcriptional indel errors are relevant to certain disease states (21) (22) (23) (24) (25) and maybe significant for aging (26, 27) .

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