Author: Farag, Mohamed A.; Porzel, Andrea; Wessjohann, Ludger A.
Title: Unequivocal glycyrrhizin isomer determination and comparative in vitro bioactivities of root extracts in four Glycyrrhiza species Document date: 2014_5_14
ID: k7cosg5s_3
Snippet: In regard to quality control (QC) analysis of licorice roots, Glycyrrhizin (G) is often considered as the most frequently monitored metabolite via HPLC. Nevertheless, for HPLC, it is rather difficult to resolve the 18a and 18b stereoisomers satisfactorily due to the very similar properties of these epimers. Only a few papers report procedures to distinguish a-GA and b-GA, using chiral separation, HPTLC and gel electrophoresis [13, 14] , which all.....
Document: In regard to quality control (QC) analysis of licorice roots, Glycyrrhizin (G) is often considered as the most frequently monitored metabolite via HPLC. Nevertheless, for HPLC, it is rather difficult to resolve the 18a and 18b stereoisomers satisfactorily due to the very similar properties of these epimers. Only a few papers report procedures to distinguish a-GA and b-GA, using chiral separation, HPTLC and gel electrophoresis [13, 14] , which all require elaborate chromatography for a separation of the isomers. Interest in both G biological activity and improving QC analysis of licorice samples, drives the development of faster, stable and accurate methods for reliable G isomer assignment in licorice extracts.
Search related documents:
Co phrase search for related documents- biological activity and quality control: 1
- chiral separation and quality control: 1
Co phrase search for related documents, hyperlinks ordered by date