Author: Jain, K.K.
Title: Synthetic Biology and Personalized Medicine Document date: 2012_8_16
ID: jejgkcql_11
Snippet: Biosensing is an important activity due to myriads of cell signaling pathways and circuits in cells. It is an important component of two-way communication between implanted engineered cells and natural cells of the body. Examples of synthetic biosensing are [9] : (1) Transcriptional biosensors are built by linking environment-responsive promoters to engineered gene circuits for programmed transcription. (2) Translational biosensors are typically .....
Document: Biosensing is an important activity due to myriads of cell signaling pathways and circuits in cells. It is an important component of two-way communication between implanted engineered cells and natural cells of the body. Examples of synthetic biosensing are [9] : (1) Transcriptional biosensors are built by linking environment-responsive promoters to engineered gene circuits for programmed transcription. (2) Translational biosensors are typically built by linking RNA aptamer domains to RNA regulatory domains. (3) Posttranslational biosensors consist of membrane-bound protein receptors that trigger signal transduction cascades.
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