Author: Noh, Heeju; Shoemaker, Jason E; Gunawan, Rudiyanto
Title: Network perturbation analysis of gene transcriptional profiles reveals protein targets and mechanism of action of drugs and influenza A viral infection Document date: 2018_4_6
ID: j80hnhpb_34
Snippet: In differential gene expression (DE) analysis, we calculated the log 2 FC differential expression of each protein in the PGRN, as described in section Gene expression data above. Here, we used the log 2 FC values directly as the target scores. Correspondingly, we ranked the candidate protein targets in decreasing magnitude of the log 2 FC gene expression values......
Document: In differential gene expression (DE) analysis, we calculated the log 2 FC differential expression of each protein in the PGRN, as described in section Gene expression data above. Here, we used the log 2 FC values directly as the target scores. Correspondingly, we ranked the candidate protein targets in decreasing magnitude of the log 2 FC gene expression values.
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