Selected article for: "ATP dependent dna helicase and dna helicase"
Author: Kaliamurthi, Satyavani; Selvaraj, Gurudeeban; Kaushik, Aman Chandra; Gu, Ke-Ren; Wei, Dong-Qing
Title: Designing of CD8(+) and CD8(+)-overlapped CD4(+) epitope vaccine by targeting late and early proteins of human papillomavirus
  • Document date: 2018_10_2
    • ID: j0runrkf_1
    Snippet: Human papillomavirus (HPV) is an oncogenic, mucosa-infecting, and etiologic agent that causes over 90% of cases of cervical cancer in the world. 1, 2 The genome of HPV consists of three regions, viz, noncoding region (extended control), and nonstructural (E1-E7) and structural regions (L1, L2) of the open reading frames. 3, 4 Briefly, E1 protein is the ATP-dependent DNA helicase which is involved in replication. E2 protein acts as a regulator of .....
    Document: Human papillomavirus (HPV) is an oncogenic, mucosa-infecting, and etiologic agent that causes over 90% of cases of cervical cancer in the world. 1, 2 The genome of HPV consists of three regions, viz, noncoding region (extended control), and nonstructural (E1-E7) and structural regions (L1, L2) of the open reading frames. 3, 4 Briefly, E1 protein is the ATP-dependent DNA helicase which is involved in replication. E2 protein acts as a regulator of viral gene transcription and genome replication. E4 and E5 proteins are involved in the early and late phases of the virus life cycle and immune modulation.

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