Author: Kang, Na-Jin; Koo, Dong-Hwan; Kang, Gyeoung-Jin; Han, Sang-Chul; Lee, Bang-Won; Koh, Young-Sang; Hyun, Jin-Won; Lee, Nam-Ho; Ko, Mi-Hee; Kang, Hee-Kyoung; Yoo, Eun-Sook
Title: Dieckol, a Component of Ecklonia cava, Suppresses the Production of MDC/CCL22 via Down-Regulating STAT1 Pathway in Interferon-? Stimulated HaCaT Human Keratinocytes Document date: 2015_5_1
ID: k6f3luil_29
Snippet: In the present study, we investigated the anti-inflammatory effect of dieckol and its possible action mechanisms in the category of skin inflammation including atopic dermatitis. First we examined the effect of the two phlorotannin compounds (eckol and dieckol) on the MDC production in IFN-γ-stimulated Ha-CaT keratinocytes. Dieckol suppressed MDC production in a dose dependent manner, while eckol was not effective......
Document: In the present study, we investigated the anti-inflammatory effect of dieckol and its possible action mechanisms in the category of skin inflammation including atopic dermatitis. First we examined the effect of the two phlorotannin compounds (eckol and dieckol) on the MDC production in IFN-γ-stimulated Ha-CaT keratinocytes. Dieckol suppressed MDC production in a dose dependent manner, while eckol was not effective.
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