Title: Macrophages genetically resistant to mouse hepatitis virus converted in vitro to susceptible macrophages Document date: 1976_3_1
ID: k3ddpja5_4
Snippet: It was then necessary to evaluate the stability and effectiveness of the presumptive lymphokine, which will be referred to as the susceptibility factor. Table II shows the effect of different concentrations of this factor on the increased susceptibility of C3H macrophages. Although there was some decrease of activity at a 1% dilution, there was still a 100-fold increase in susceptibility. Undiluted susceptibility factor frozen at -70°C for 1 wk .....
Document: It was then necessary to evaluate the stability and effectiveness of the presumptive lymphokine, which will be referred to as the susceptibility factor. Table II shows the effect of different concentrations of this factor on the increased susceptibility of C3H macrophages. Although there was some decrease of activity at a 1% dilution, there was still a 100-fold increase in susceptibility. Undiluted susceptibility factor frozen at -70°C for 1 wk was tested at a 10% concentration and again produced a 1,000-fold increase in susceptibility.
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