Author: Jain, K.K.
Title: Synthetic Biology and Personalized Medicine Document date: 2012_8_16
ID: jejgkcql_27
Snippet: Synthetic biology provides the following advantages over conventional techniques for drug discovery and development: (1) Synthetic biology can enable the design of cells to screen drug molecules and reduce drug discovery time/expense. (2) Metabolic pathways can be more precisely regulated in synthetic organisms and manipulated by molecular tools. (3) Parallel to recombinant E. colibased biotechnology drug production, synthetic biology enables red.....
Document: Synthetic biology provides the following advantages over conventional techniques for drug discovery and development: (1) Synthetic biology can enable the design of cells to screen drug molecules and reduce drug discovery time/expense. (2) Metabolic pathways can be more precisely regulated in synthetic organisms and manipulated by molecular tools. (3) Parallel to recombinant E. colibased biotechnology drug production, synthetic biology enables redesigning of cells to produce desirable molecules with higher efficacy and lower toxicity. (4) Data accumulated with advances in sequencing can be used for combining synthetic biology with personalized medicine. (5) Reduction of cost of biologicals, particularly therapeutic proteins. (6) Potential for production of synthetic therapeutic proteins.
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