Author: Szczawinska-Poplonyk, Aleksandra; Jonczyk-Potoczna, Katarzyna; Ossowska, Lidia; Breborowicz, Anna; Bartkowska-Sniatkowska, Alicja; Wachowiak, Jacek
Title: Cytomegalovirus pneumonia as the first manifestation of severe combined immunodeficiency Document date: 2014_10_14
ID: ixm3uuai_14
Snippet: Severe interstitial pneumonia of viral, particularly CMV, etiology in an infant, apart from lymphopenia and hypogammaglobulinemia, should alert physicians to the significance of signs which might suggest the presence of this life-threatening immune deficiency. While the chest X-ray and HRCT imaging findings are usually non-specific, the patient's age and the immune status correlate with the etiology of pneumonia and limit the spectrum of differen.....
Document: Severe interstitial pneumonia of viral, particularly CMV, etiology in an infant, apart from lymphopenia and hypogammaglobulinemia, should alert physicians to the significance of signs which might suggest the presence of this life-threatening immune deficiency. While the chest X-ray and HRCT imaging findings are usually non-specific, the patient's age and the immune status correlate with the etiology of pneumonia and limit the spectrum of differential diagnoses [13] . This is the first report on severe combined immunodeficiency which indicates the prevalence of cytomegalovirus etiology of respiratory tract infection in affected children. Given the significant impact of pulmonary CMV infection in SCID children, establishing an accurate etiological diagnosis is of essential importance in instituting the specific treatment and improving the outcome.
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