Author: Magnusson, Jesper; Westin, Johan; Andersson, Lars-Magnus; Lindh, Magnus; Brittain-Long, Robin; Nordén, Rickard; Riise, Gerdt C.
Title: Viral Respiratory Tract Infection During the First Postoperative Year Is a Risk Factor for Chronic Rejection After Lung Transplantation Document date: 2018_7_11
ID: jtgcj91t_8
Snippet: Chronic lung allograft dysfunction was defined as an irreversible loss of at least 20% from baseline of forced expiratory volume during the first second, if other reasons for the decline were excluded. When forced vital capacity was reduced with at least 20%, or the total lung capacity was reduced by at least 10% the function loss was considered to be predominantly restrictive. 14 Lung function was screened weekly using a home spirometer and a co.....
Document: Chronic lung allograft dysfunction was defined as an irreversible loss of at least 20% from baseline of forced expiratory volume during the first second, if other reasons for the decline were excluded. When forced vital capacity was reduced with at least 20%, or the total lung capacity was reduced by at least 10% the function loss was considered to be predominantly restrictive. 14 Lung function was screened weekly using a home spirometer and a conventional spirometry was performed if a loss of more than 10% in forced expiratory volume during the first second or forced vital capacity was identified. This was arranged by the transplant nurses as part of the clinical routine. Two experienced transplant pulmonologists reviewed each patient separately for CLAD development using all available spirometry data. The results were compared, and a consensus was reached on discrepancies. Graft loss was defined as either death or retransplantation.
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