Author: Kim, Eun; Erdos, Geza; Huang, Shaohua; Kenniston, Thomas; Falo, Louis D.; Gambotto, Andrea
Title: Preventative Vaccines for Zika Virus Outbreak: Preliminary Evaluation Document date: 2016_10_3
ID: jzcyxjxt_28
Snippet: Supplementary data to this article can be found online at http://dx. doi.org/10.1016/j.ebiom.2016.09.028. Fig. 3 . Protection from ZIKV infection in neonatal mice by maternal immunization with Ad5.ZIKV-Efl and MNZ.ZIKV-rEfl. Pups were obtained by mating nonimmunized males with immunized females at five weeks after prime vaccination. Pups were challenged intraperitoneally at seven days after birth with ZIKV DAKAR41542 (10 5 pfu/50 μl). Body weigh.....
Document: Supplementary data to this article can be found online at http://dx. doi.org/10.1016/j.ebiom.2016.09.028. Fig. 3 . Protection from ZIKV infection in neonatal mice by maternal immunization with Ad5.ZIKV-Efl and MNZ.ZIKV-rEfl. Pups were obtained by mating nonimmunized males with immunized females at five weeks after prime vaccination. Pups were challenged intraperitoneally at seven days after birth with ZIKV DAKAR41542 (10 5 pfu/50 μl). Body weight (a) and survival (b) were monitored for 15 days post-infection. Statistically significant differences (Tukey's test or log-rank (Mantel-Cox) test) are marked by bars and asterisks. *, P b 0.05; **, P b 0.01; ***, P b 0.001.
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