Title: 2015 ACVIM Forum Research Abstract Program Document date: 2015_5_27
ID: 3pnuj5ru_141
Snippet: The results showed that doxorubicin induced left ventricular diastolic and systolic dysfunction in rabbits, which could not be prevented by concomitant treatment with carvedilol, cyclosporine-A or sildenafil citrate. Two-dimensional (2D) echocardiography has been widely used for years to assess left ventricle (LV) systolic function. However, there are some limitations by using the conventional measurement of LV ejection fraction (EF). Two-dimensi.....
Document: The results showed that doxorubicin induced left ventricular diastolic and systolic dysfunction in rabbits, which could not be prevented by concomitant treatment with carvedilol, cyclosporine-A or sildenafil citrate. Two-dimensional (2D) echocardiography has been widely used for years to assess left ventricle (LV) systolic function. However, there are some limitations by using the conventional measurement of LV ejection fraction (EF). Two-dimensional speckle tracking imaging is a simplified and angle-independent echocardiographic tool which has been recently used for the evaluation of the quantitative global and regional ventricular functions. Syngo Velocity Vector Imaging (VVI) is a speckle tracking-based method for direct analysis of myocardial motion. The purpose of this study was to investigate the left ventricle systolic function (septal, free wall and global) by using VVI in healthy awake Beagle dogs.
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