Title: 2015 ACVIM Forum Research Abstract Program Document date: 2015_5_27
ID: 3pnuj5ru_259
Snippet: Methods: Five healthy purpose-bred hound dogs were enrolled. In Experiment 1, dogs received a single 0.1 mg/kg dose orally. Blood was collected at 0, 0.5, 1, 2, 4, 6, 12, 24, 48, and 72 hours. In Experiment 2, dogs received 0.1 mg/kg daily for 5 days. Blood was collected at 0, 3, 6, 24, 27, 30, 48, 51, 54, 72, 75, 78, 96, 96.5, 97, 98, 100, 102, 108, 120, 144 , and 168 hours. Samples were analyzed using a validated LC/MS/MS assay and evaluated vi.....
Document: Methods: Five healthy purpose-bred hound dogs were enrolled. In Experiment 1, dogs received a single 0.1 mg/kg dose orally. Blood was collected at 0, 0.5, 1, 2, 4, 6, 12, 24, 48, and 72 hours. In Experiment 2, dogs received 0.1 mg/kg daily for 5 days. Blood was collected at 0, 3, 6, 24, 27, 30, 48, 51, 54, 72, 75, 78, 96, 96.5, 97, 98, 100, 102, 108, 120, 144 , and 168 hours. Samples were analyzed using a validated LC/MS/MS assay and evaluated via non-compartmental analysis.
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