2015 ACVIM Forum Research Abstract Program

There were significant correlations between the three cortisol concentrations with the best correlation being seen between then pre-pill and post-pill (r = 0.760, p < 0.000) results. There were also significant but weak correlations between the pre (r = 0.399, p < 0.000), the post (r = 0.350, p < 0.000) and the post ACTH (r = 0.246, p < 0.012) cortisol and the total score from the owner questionnaire. On multivariate analysis male neutered dogs were found to have significantly increased pre-pill cortisol (p < 0.0027) and post-pill cortisol (p < 0.044) when compared to female entire dogs and all dogs respectively. When dogs were receiving the current dose for more than 3 months, the cortisol was significantly lower at both the post-pill (P < 0.037) and post ACTH (P < 0.000) cortisol time-points. None of the other variables were associated with an effect on the three cortisol results.