Title: 2015 ACVIM Forum Research Abstract Program Document date: 2015_5_27
ID: 3pnuj5ru_769
Snippet: Pharmacokinetics of same BW-based PDS dose were found different in small and large breed dogs. Therefore clinicians are suggested to adjust the dose by considering PK difference of PDS based on BSA or BW. Chronic bronchitis (CB) is a common disease of dogs resulting in a chronic cough (≥ 2 months) and inflammation of the lower airways. Adverse effects and risk of secondary infection associated with lifelong steroid administration prompt investi.....
Document: Pharmacokinetics of same BW-based PDS dose were found different in small and large breed dogs. Therefore clinicians are suggested to adjust the dose by considering PK difference of PDS based on BSA or BW. Chronic bronchitis (CB) is a common disease of dogs resulting in a chronic cough (≥ 2 months) and inflammation of the lower airways. Adverse effects and risk of secondary infection associated with lifelong steroid administration prompt investigation into alternative therapies. Neurogenic pathways mediated by tachykinins binding neurokinin (NK) 1 receptors may contribute to airway inflammation. Maropitant (Cerenia Ò ), a NK-1 receptor antagonist, has been used for CB based on anecdotal improvement without supporting evidence. We hypothesized that maropitant would blunt clinical signs and airway inflammation associated with CB.
Search related documents:
Co phrase search for related documents- adverse effect and chronic cough: 1, 2
- adverse effect and common disease: 1
- adverse effect and evidence support: 1, 2
- adverse effect and receptor antagonist: 1, 2
- adverse effect and risk adverse effect: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17
- adverse effect and secondary infection: 1, 2, 3
- airway inflammation and alternative therapy: 1
- airway inflammation and chronic bronchitis: 1, 2, 3, 4, 5, 6, 7, 8, 9
- airway inflammation and chronic cough: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10
- airway inflammation and common disease: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12
- airway inflammation and evidence support: 1, 2, 3
- airway inflammation and low airway: 1, 2, 3
- airway inflammation and low airway inflammation: 1, 2
- airway inflammation and receptor antagonist: 1, 2, 3
- airway inflammation and secondary infection: 1, 2, 3, 4
- airway inflammation contribute and evidence support: 1
- airway inflammation contribute and secondary infection: 1
- alternative therapy and chronic bronchitis: 1
- alternative therapy and chronic cough: 1
Co phrase search for related documents, hyperlinks ordered by date