2015 ACVIM Forum Research Abstract Program

Feeding conditions did not impact TRH stimulation test results, but ACTH concentrations increased by a lower magnitude when testing was combined with the OST. Combination testing is not recommended at this time. Several tests have been evaluated in horses and humans for quantifying systemic insulin resistance, but many of these tests have not been evaluated for agreement. This study evaluated the agreement between four methods of insulin sensitivity testing in horses, including basal serum insulin and glucose concentration, oral sugar test (OST), combined glucose-insulin test (CGIT), and the insulin-modified frequently sampled intravenous glucose tolerance test (FSIGTT).