Title: 2015 ACVIM Forum Research Abstract Program Document date: 2015_5_27
ID: 3pnuj5ru_272
Snippet: Median serum TSH concentration in the 786 hyperthyroid cats (0.03 ng/ml) was significantly (P < 0.001) lower than median values in the normal cats (0.05 ng/ml) and the euthyroid cats with suspected thyroid disease (0.06 ng/ml). No significant difference existed between the median concentrations of T4, T3, free T4, or TSH in clinically normal cats and the values in the suspect cats. Only 14 (1.8%) hyperthyroid cats had measurable TSH values, where.....
Document: Median serum TSH concentration in the 786 hyperthyroid cats (0.03 ng/ml) was significantly (P < 0.001) lower than median values in the normal cats (0.05 ng/ml) and the euthyroid cats with suspected thyroid disease (0.06 ng/ml). No significant difference existed between the median concentrations of T4, T3, free T4, or TSH in clinically normal cats and the values in the suspect cats. Only 14 (1.8%) hyperthyroid cats had measurable TSH values, whereas 98.2% had TSH concentrations at or below the level of quantification (<0.03). In contrast, TSH concentrations were detectable in 71 (59%) of the 120 normal cats and in 24 (86%) of the 28 euthyroid cats. Overall, the sensitivity of serum TSH as a diagnostic test for hyperthyroidism was 98.2%, but the test specificity was only 49.3%.
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