2015 ACVIM Forum Research Abstract Program

Syme 2 , Jonathan Elliott 2 , Joy Archer 1 . 1 University of Cambridge, Cambridge, UK, 2 Royal Veterinary College, London, UK Several studies have attempted to identify reliable biomarkers of CKD in hyperthyroid cats, with little success to date. Low plasma total globulin concentration was independently associated with the development of azotemia following treatment of hyperthyroidism in one study, which suggests that dysproteinemia is a marker of concurrent CKD. Characterisation of dysproteinemia is possible by serum protein electrophoresis (SPE). Further investigation of the changes that occur in the globulin fraction in hyperthyroid cats, and the possible association of these changes with the presence of concurrent CKD, is warranted, since this might provide a novel biomarker for CKD.