Title: 2016 ACVIM Forum Research Abstract Program Document date: 2016_5_31
ID: 2y1y8jpx_201
Snippet: Viral genomes but not replication-competent viruses were detected in secondary lymphoid tissues (i.e. spleen) on day 39. Replication-competent virus was not detected in peripheral blood, saliva, urine, or feces. Viral genomes in secondary lymphoid tissues without concurrent replication-competent virus is a finding similar to that in mice and primates, and reflects the propensity of Maraba virus to be taken up by antigen-presenting cells when deli.....
Document: Viral genomes but not replication-competent viruses were detected in secondary lymphoid tissues (i.e. spleen) on day 39. Replication-competent virus was not detected in peripheral blood, saliva, urine, or feces. Viral genomes in secondary lymphoid tissues without concurrent replication-competent virus is a finding similar to that in mice and primates, and reflects the propensity of Maraba virus to be taken up by antigen-presenting cells when delivered systemically, making it an ideal vector for boosting immune responses.
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