Selected article for: "amino acid and autoimmune disease"
Title: 2015 ACVIM Forum Research Abstract Program
  • Document date: 2015_5_27
    • ID: 3pnuj5ru_513
    Snippet: The frequency of the variant allele was significantly higher in dogs with autoimmune disease than in control dogs (0.23 vs. 0.08, P < 0.001), and ranged from 0.37 in dogs with IMPA to 0.15 in dogs with atopic dermatitis. The alternate allele causes two non-synonymous substitutions resulting in p.Phe62Leu and p.Asn66Asp amino acid changes. These mutations occur in an antigen binding pocket of the homologous human protein......
    Document: The frequency of the variant allele was significantly higher in dogs with autoimmune disease than in control dogs (0.23 vs. 0.08, P < 0.001), and ranged from 0.37 in dogs with IMPA to 0.15 in dogs with atopic dermatitis. The alternate allele causes two non-synonymous substitutions resulting in p.Phe62Leu and p.Asn66Asp amino acid changes. These mutations occur in an antigen binding pocket of the homologous human protein.

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