Selected article for: "general linear model and linear model"
Title: 2016 ACVIM Forum Research Abstract Program
  • Document date: 2016_5_31
    • ID: 2y1y8jpx_472
    Snippet: This was a randomized double blind placebo controlled study. Samples were collected from 21 dogs with PAOEM, which were treated with topical AZ (1 mL AZ solution at the concentration of 50 µg/mL, SID) or placebo (1 mL sterile 0.9% saline) for 56 days. All dogs were prescribed standard PAOEM treatment and regularly evaluated by their veterinarians. For the purpose of this study dogs were clinically evaluated and ear canal samples taken on days 0,.....
    Document: This was a randomized double blind placebo controlled study. Samples were collected from 21 dogs with PAOEM, which were treated with topical AZ (1 mL AZ solution at the concentration of 50 µg/mL, SID) or placebo (1 mL sterile 0.9% saline) for 56 days. All dogs were prescribed standard PAOEM treatment and regularly evaluated by their veterinarians. For the purpose of this study dogs were clinically evaluated and ear canal samples taken on days 0, 7, 14, 21, 28, 42 and 56. Samples were obtained by rinsing ear canals with 30 mL of sterile saline. The concentration of BHL, HHL and OdDHL in ng/mL was determined by liquid chromatography coupled with tandem mass spectrometry. Bacteriological and cytological analyses were performed. Clinical signs (ear canal edema, pain, stenosis and erythema) were graded from 0-4; grades were then summarized to form a single clinical sign grade. Data were analyzed using linear mixed effects model for continuous outcomes and general linear mixed effects model for the binary outcomes; a P-value of <0.05 was considered significant.

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